Melatonin ameliorates hypoglycemic stress‐induced brain endothelial tight junction injury by inhibiting protein nitration of TP53‐induced glycolysis and apoptosis regulator

Severe hypoglycemia has a detrimental impact on the cerebrovasculature, but the molecular events that lead to the disruption of the integrity of the tight junctions remain unclear. Here, we report that the microvessel integrity was dramatically compromised (59.41% of wild‐type mice) in TP53‐induced...

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Detalles Bibliográficos
Autores principales: Wang, Cheng‐kun, Ahmed, Muhammad Masood, Jiang, Quan, Lu, Nan‐nan, Tan, Chao, Gao, Yin‐ping, Mahmood, Qaisar, Chen, Dan‐yang, Fukunaga, Kohji, Li, Mei, Chen, Zhong, Wilcox, Christopher S., Lu, Ying‐mei, Qin, Zheng‐hong, Han, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656838/
https://www.ncbi.nlm.nih.gov/pubmed/28776759
http://dx.doi.org/10.1111/jpi.12440

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