Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement

Nucleic acids are excellent building blocks to enable switchable character in supramolecular polymer materials because of their inherent dynamic character and potential for orthogonal self‐assembly. Herein, DNA‐grafted squaramide bola‐amphiphiles are used in a multicomponent supramolecular polymer s...

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Detalles Bibliográficos
Autores principales: Noteborn, Willem E. M., Saez Talens, Victorio, Kieltyka, Roxanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656891/
https://www.ncbi.nlm.nih.gov/pubmed/28834068
http://dx.doi.org/10.1002/cbic.201700441
Descripción
Sumario:Nucleic acids are excellent building blocks to enable switchable character in supramolecular polymer materials because of their inherent dynamic character and potential for orthogonal self‐assembly. Herein, DNA‐grafted squaramide bola‐amphiphiles are used in a multicomponent supramolecular polymer system and it is shown that they can be addressed by DNAlabeled gold nanoparticles (5 and 15 nm) through sequence complementarity. These nanoparticles can be selectively erased or rewritten on‐demand by means of DNA‐strand displacement.

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