Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement

Nucleic acids are excellent building blocks to enable switchable character in supramolecular polymer materials because of their inherent dynamic character and potential for orthogonal self‐assembly. Herein, DNA‐grafted squaramide bola‐amphiphiles are used in a multicomponent supramolecular polymer s...

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Detalles Bibliográficos
Autores principales: Noteborn, Willem E. M., Saez Talens, Victorio, Kieltyka, Roxanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656891/
https://www.ncbi.nlm.nih.gov/pubmed/28834068
http://dx.doi.org/10.1002/cbic.201700441
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author Noteborn, Willem E. M.
Saez Talens, Victorio
Kieltyka, Roxanne E.
author_facet Noteborn, Willem E. M.
Saez Talens, Victorio
Kieltyka, Roxanne E.
author_sort Noteborn, Willem E. M.
collection PubMed
description Nucleic acids are excellent building blocks to enable switchable character in supramolecular polymer materials because of their inherent dynamic character and potential for orthogonal self‐assembly. Herein, DNA‐grafted squaramide bola‐amphiphiles are used in a multicomponent supramolecular polymer system and it is shown that they can be addressed by DNAlabeled gold nanoparticles (5 and 15 nm) through sequence complementarity. These nanoparticles can be selectively erased or rewritten on‐demand by means of DNA‐strand displacement.
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spelling pubmed-56568912017-11-01 Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement Noteborn, Willem E. M. Saez Talens, Victorio Kieltyka, Roxanne E. Chembiochem Communications Nucleic acids are excellent building blocks to enable switchable character in supramolecular polymer materials because of their inherent dynamic character and potential for orthogonal self‐assembly. Herein, DNA‐grafted squaramide bola‐amphiphiles are used in a multicomponent supramolecular polymer system and it is shown that they can be addressed by DNAlabeled gold nanoparticles (5 and 15 nm) through sequence complementarity. These nanoparticles can be selectively erased or rewritten on‐demand by means of DNA‐strand displacement. John Wiley and Sons Inc. 2017-09-07 2017-10-18 /pmc/articles/PMC5656891/ /pubmed/28834068 http://dx.doi.org/10.1002/cbic.201700441 Text en © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Communications
Noteborn, Willem E. M.
Saez Talens, Victorio
Kieltyka, Roxanne E.
Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement
title Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement
title_full Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement
title_fullStr Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement
title_full_unstemmed Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement
title_short Reversible Loading of Nanoscale Elements on a Multicomponent Supramolecular Polymer System by Using DNA Strand Displacement
title_sort reversible loading of nanoscale elements on a multicomponent supramolecular polymer system by using dna strand displacement
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656891/
https://www.ncbi.nlm.nih.gov/pubmed/28834068
http://dx.doi.org/10.1002/cbic.201700441
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AT kieltykaroxannee reversibleloadingofnanoscaleelementsonamulticomponentsupramolecularpolymersystembyusingdnastranddisplacement

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