Release of Enzymatically Active Deubiquitinating Enzymes upon Reversible Capture by Disulfide Ubiquitin Reagents

Deubiquitinating enzymes (DUBs) catalyze the cleavage of ubiquitin from target proteins. Ubiquitin is post‐translationally attached to proteins and serves as an important regulatory signal for key cellular processes. In this study, novel activity‐based probes to study DUBs were synthesized that comp...

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Detalles Bibliográficos
Autores principales: de Jong, Annemieke, Witting, Katharina, Kooij, Raymond, Flierman, Dennis, Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656918/
https://www.ncbi.nlm.nih.gov/pubmed/28841265
http://dx.doi.org/10.1002/anie.201706738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656918/
https://www.ncbi.nlm.nih.gov/pubmed/28841265
http://dx.doi.org/10.1002/anie.201706738

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