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Detection and quantification of mitochondrial DNA deletions from next-generation sequence data
BACKGROUND: Chromosomal deletions represent an important class of human genetic variation. Various methods have been developed to mine “next-generation” sequencing (NGS) data to detect deletions and quantify their clonal abundances. These methods have focused almost exclusively on the nuclear genome...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657046/ https://www.ncbi.nlm.nih.gov/pubmed/29072135 http://dx.doi.org/10.1186/s12859-017-1821-7 |