McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes

Transcriptional enhancers regulate spatio-temporal gene expression. While genomic assays can identify putative enhancers en masse, assigning target genes is a complex challenge. We devised a machine learning approach, McEnhancer, which links target genes to putative enhancers via a semi-supervised l...

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Detalles Bibliográficos
Autores principales: Hafez, Dina, Karabacak, Aslihan, Krueger, Sabrina, Hwang, Yih-Chii, Wang, Li-San, Zinzen, Robert P., Ohler, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657048/
https://www.ncbi.nlm.nih.gov/pubmed/29070071
http://dx.doi.org/10.1186/s13059-017-1316-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657048/
https://www.ncbi.nlm.nih.gov/pubmed/29070071
http://dx.doi.org/10.1186/s13059-017-1316-x

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