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McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes
Transcriptional enhancers regulate spatio-temporal gene expression. While genomic assays can identify putative enhancers en masse, assigning target genes is a complex challenge. We devised a machine learning approach, McEnhancer, which links target genes to putative enhancers via a semi-supervised l...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657048/ https://www.ncbi.nlm.nih.gov/pubmed/29070071 http://dx.doi.org/10.1186/s13059-017-1316-x |