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Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice

BACKGROUND: Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the outbreak and spread of this disease. METHODS: In this study, we generated MARV vir...

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Detalles Bibliográficos
Autores principales: Gai, Weiwei, Zheng, Xuexing, Wang, Chong, Wang, Hualei, Zhao, Yongkun, Wang, Qi, Wong, Gary, Zhang, Weijiao, Feng, Na, Qiu, Boning, Chi, Hang, Li, Nan, Wang, Tiecheng, Gao, Yuwei, Shan, Junjie, Yang, Songtao, Xia, Xianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657058/
https://www.ncbi.nlm.nih.gov/pubmed/29070075
http://dx.doi.org/10.1186/s12985-017-0869-3