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An improved burden-test pipeline for identifying associations from rare germline and somatic variants

BACKGROUND: Identifying rare germline and somatic variants associated with cancer progression is an important research topic in cancer genomics. Although many approaches are proposed for rare variant association study, they are not fit for cancer sequencing data due to multiple issues, such as overl...

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Detalles Bibliográficos
Autores principales:	Geng, Yu, Zhao, Zhongmeng, Zhang, Xuanping, Wang, Wenke, Cui, Xingjian, Ye, Kai, Xiao, Xiao, Wang, Jiayin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657102/ https://www.ncbi.nlm.nih.gov/pubmed/29513197 http://dx.doi.org/10.1186/s12864-017-4133-4

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