Sex influences eQTL effects of SLE and Sjögren’s syndrome-associated genetic polymorphisms

BACKGROUND: Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are autoimmune disorders characterized by autoantibodies, dysregulated B cells, and notably high female-to-male incidence ratios. Genome-wide association studies have identified several susceptibility SNPs for both d...

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Detalles Bibliográficos
Autores principales: Lindén, Magdalena, Ramírez Sepúlveda, Jorge I., James, Tojo, Thorlacius, Gudny Ella, Brauner, Susanna, Gómez-Cabrero, David, Olsson, Tomas, Kockum, Ingrid, Wahren-Herlenius, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657123/
https://www.ncbi.nlm.nih.gov/pubmed/29070082
http://dx.doi.org/10.1186/s13293-017-0153-7

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