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Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice

Highly pathogenic avian influenza (HPAI) H5N8 virus has caused considerable economic losses to poultry industry and poses a great threat to public health. Our previous study revealed two genetically similar HPAI H5N8 viruses displaying completely different virulence in mice. However, the molecular b...

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Detalles Bibliográficos
Autores principales:	Wang, Xiao, Chen, Sujuan, Wang, Dandan, Zha, Xixin, Zheng, Siwen, Qin, Tao, Ma, Wenjun, Peng, Daxin, Liu, Xiufan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657129/ https://www.ncbi.nlm.nih.gov/pubmed/29070059 http://dx.doi.org/10.1186/s13567-017-0471-0

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