Cargando…

Choroidal melanoma: A short review with an Indian perspective

Choroidal melanoma (CM), the most common intraocular tumor in adults, is still a rarity in Asia. Having a high propensity for metastasis with a poor survival, recognizing it early is essential. Although it has typical clinical features, there are instances of simulating lesions. Fine-needle aspirati...

Descripción completa

Detalles Bibliográficos
Autores principales: Pal, Bikramjit P., Garge, Saili, Khetan, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657153/
https://www.ncbi.nlm.nih.gov/pubmed/29118486
http://dx.doi.org/10.4103/ojo.OJO_234_2016
_version_ 1783273830407471104
author Pal, Bikramjit P.
Garge, Saili
Khetan, Vikas
author_facet Pal, Bikramjit P.
Garge, Saili
Khetan, Vikas
author_sort Pal, Bikramjit P.
collection PubMed
description Choroidal melanoma (CM), the most common intraocular tumor in adults, is still a rarity in Asia. Having a high propensity for metastasis with a poor survival, recognizing it early is essential. Although it has typical clinical features, there are instances of simulating lesions. Fine-needle aspiration biopsy can be a valuable tool not only to confirm our clinical suspicion but also aid in prognosticating it. From days of histopathological prognostic markers, we are moving on to genetic markers which are reliably providing insights, helping us in providing a better care for our patients. Eye preservation has taken an all new important meaning in CM with many centers opting for different modalities of radiation. Herein, we try to provide a short synopsis of CM looking into its epidemiology, clinical features, diagnosis, and management. We also look briefly into the role of fine-needle biopsy in managing CM. Being a tertiary referral ocular center in India, we do come across CM; we have shared the preliminary reports of our analysis of managing CM over a 9-year period.
format Online
Article
Text
id pubmed-5657153
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-56571532017-11-08 Choroidal melanoma: A short review with an Indian perspective Pal, Bikramjit P. Garge, Saili Khetan, Vikas Oman J Ophthalmol Review Article Choroidal melanoma (CM), the most common intraocular tumor in adults, is still a rarity in Asia. Having a high propensity for metastasis with a poor survival, recognizing it early is essential. Although it has typical clinical features, there are instances of simulating lesions. Fine-needle aspiration biopsy can be a valuable tool not only to confirm our clinical suspicion but also aid in prognosticating it. From days of histopathological prognostic markers, we are moving on to genetic markers which are reliably providing insights, helping us in providing a better care for our patients. Eye preservation has taken an all new important meaning in CM with many centers opting for different modalities of radiation. Herein, we try to provide a short synopsis of CM looking into its epidemiology, clinical features, diagnosis, and management. We also look briefly into the role of fine-needle biopsy in managing CM. Being a tertiary referral ocular center in India, we do come across CM; we have shared the preliminary reports of our analysis of managing CM over a 9-year period. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5657153/ /pubmed/29118486 http://dx.doi.org/10.4103/ojo.OJO_234_2016 Text en Copyright: © 2017 Oman Ophthalmic Society http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Pal, Bikramjit P.
Garge, Saili
Khetan, Vikas
Choroidal melanoma: A short review with an Indian perspective
title Choroidal melanoma: A short review with an Indian perspective
title_full Choroidal melanoma: A short review with an Indian perspective
title_fullStr Choroidal melanoma: A short review with an Indian perspective
title_full_unstemmed Choroidal melanoma: A short review with an Indian perspective
title_short Choroidal melanoma: A short review with an Indian perspective
title_sort choroidal melanoma: a short review with an indian perspective
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657153/
https://www.ncbi.nlm.nih.gov/pubmed/29118486
http://dx.doi.org/10.4103/ojo.OJO_234_2016
work_keys_str_mv AT palbikramjitp choroidalmelanomaashortreviewwithanindianperspective
AT gargesaili choroidalmelanomaashortreviewwithanindianperspective
AT khetanvikas choroidalmelanomaashortreviewwithanindianperspective