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N (6)-Hydroperoxymethyladenosine: a new intermediate of chemical oxidation of N(6)-methyladenosine mediated by bicarbonate-activated hydrogen peroxide
N (6)-Methyladenosine (m(6)A) represents a relatively abundant modification in eukaryotic RNA. Because m(6)A has similar properties to adenosine and a low reactivity, limited research has been focused on this nucleoside. In this study, we revealed an important intermediate in the oxidation of m(6)A...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657413/ https://www.ncbi.nlm.nih.gov/pubmed/29142684 http://dx.doi.org/10.1039/c5sc00484e |