N (6)-Hydroperoxymethyladenosine: a new intermediate of chemical oxidation of N(6)-methyladenosine mediated by bicarbonate-activated hydrogen peroxide

N (6)-Methyladenosine (m(6)A) represents a relatively abundant modification in eukaryotic RNA. Because m(6)A has similar properties to adenosine and a low reactivity, limited research has been focused on this nucleoside. In this study, we revealed an important intermediate in the oxidation of m(6)A...

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Detalles Bibliográficos
Autores principales: Wu, Jinjun, Xiao, Heng, Wang, Tianlu, Hong, Tingting, Fu, Boshi, Bai, Dongsheng, He, Zhiyong, Peng, Shuang, Xing, Xiwen, Hu, Jianlin, Guo, Pu, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657413/
https://www.ncbi.nlm.nih.gov/pubmed/29142684
http://dx.doi.org/10.1039/c5sc00484e

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