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Src-family kinases negatively regulate NFAT signaling in resting human T cells
T cell signaling is required for activation of both natural and therapeutic T cells including chimeric antigen receptor (CAR) T cells. Identification of novel factors and pathways regulating T cell signaling may aid in development of effective T cell therapies. In resting human T cells, the majority...
Autores principales: | Baer, Alan, Colon-Moran, Winston, Xiang, Jinhua, Stapleton, Jack T., Bhattarai, Nirjal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658144/ https://www.ncbi.nlm.nih.gov/pubmed/29073235 http://dx.doi.org/10.1371/journal.pone.0187123 |
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