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Single-cell analysis identifies cellular markers of the HIV permissive cell

Cellular permissiveness to HIV infection is highly heterogeneous across individuals. Heterogeneity is also found across CD4(+) T cells from the same individual, where only a fraction of cells gets infected. To explore the basis of permissiveness, we performed single-cell RNA-seq analysis of non-infe...

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Detalles Bibliográficos
Autores principales: Rato, Sylvie, Rausell, Antonio, Muñoz, Miguel, Telenti, Amalio, Ciuffi, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658171/
https://www.ncbi.nlm.nih.gov/pubmed/29073251
http://dx.doi.org/10.1371/journal.ppat.1006678