Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy

Targeting of Toxoplasma gondii by autophagy is an effective mechanism by which host cells kill the protozoan. Thus, the parasite must avoid autophagic targeting to survive. Here we show that the mammalian cytoplasmic molecule Focal Adhesion Kinase (FAK) becomes activated during invasion of host cell...

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Detalles Bibliográficos
Autores principales: Portillo, Jose-Andres C., Muniz-Feliciano, Luis, Lopez Corcino, Yalitza, Lee, So Jung, Van Grol, Jennifer, Parsons, Sarah J., Schiemman, William P., Subauste, Carlos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658194/
https://www.ncbi.nlm.nih.gov/pubmed/29036202
http://dx.doi.org/10.1371/journal.ppat.1006671

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