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Feasibility of esophageal stent fixation with an over-the-scope-clip for malignant esophageal strictures to prevent migration

BACKGROUND AND STUDY AIMS:  Fixation of an esophageal self-expandable metal stent (SEMS) with an over-the-scope-clip (OTSC) system for a benign stricture to prevent migration has been reported. However, the efficacy of SEMS fixation with an OTSC for malignant esophageal stricture remains unclear. Th...

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Detalles Bibliográficos
Autores principales: Watanabe, Ko, Hikichi, Takuto, Nakamura, Jun, Takagi, Tadayuki, Suzuki, Rei, Sugimoto, Mitsuru, Waragai, Yuichi, Kikuchi, Hitomi, Konno, Naoki, Asama, Hiroyuki, Takasumi, Mika, Sato, Yuki, Obara, Katsutoshi, Ohira, Hiromasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658212/
https://www.ncbi.nlm.nih.gov/pubmed/29090243
http://dx.doi.org/10.1055/s-0043-111793
Descripción
Sumario:BACKGROUND AND STUDY AIMS:  Fixation of an esophageal self-expandable metal stent (SEMS) with an over-the-scope-clip (OTSC) system for a benign stricture to prevent migration has been reported. However, the efficacy of SEMS fixation with an OTSC for malignant esophageal stricture remains unclear. The aim of this retrospective study was to evaluate the feasibility of SEMS fixation with an OTSC for a malignant esophageal stricture. PATIENTS AND METHODS : Twelve patients who underwent esophageal SEMS placement and fixation with an OTSC for a malignant esophageal stricture were included in this retrospective study. The primary endpoint was technical success. The secondary endpoint was clinical success, which was defined as an improvement of at least 1 grade in the dysphagia score 1 week after SEMS placement or changes in the dysphagia score from before SEMS placement to 1 week after SEMS placement. RESULTS:  The technical success rate was 100 %. The clinical success rate was 92.3 %. In 6 mild stricture cases in which a standard peroral endoscope could be used, no migration of the SEMS was observed. The median dysphagia score before and at 1 week after SEMS placement was 3 (range 2 – 4) and 0 (0 – 4), respectively, which indicated improvement at 1 week after SEMS placement compared with before SEMS placement ( P  = 0.002). There were no adverse events associated with placement of SEMS and deployment of an OTSC. CONCLUSIONS : SEMS fixation with an OTSC is feasible for prevention of migration due to a malignant esophageal stricture.