Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection

High glucose transporter 1 (Glut1) surface expression is associated with increased glycolytic activity in activated CD4+ T cells. Phosphatidylinositide 3‐kinases (PI3K) activation measured by p‐Akt and OX40 is elevated in CD4+Glut1+ T cells from HIV+ subjects. TCR engagement of CD4+Glut1+ T cells fr...

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Detalles Bibliográficos
Autores principales: Palmer, Clovis S., Duette, Gabriel A., Wagner, Marc C. E., Henstridge, Darren C., Saleh, Suah, Pereira, Candida, Zhou, Jingling, Simar, David, Lewin, Sharon R., Ostrowski, Matias, McCune, Joseph M., Crowe, Suzanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658250/
https://www.ncbi.nlm.nih.gov/pubmed/28892135
http://dx.doi.org/10.1002/1873-3468.12843

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