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Implications for Drug Characterization in Glucose Tolerance Tests Without Insulin: Simulation Study of Power and Predictions Using Model‐Based Analysis

In antihyperglycemic drug development, drug effects are usually characterized using glucose provocations. Analyzing provocation data using pharmacometrics has shown powerful, enabling small studies. In preclinical drug development, high power is attractive due to the experiment sizes; however, insul...

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Detalles Bibliográficos
Autores principales:	Sheikh Ghadzi, SM, Karlsson, MO, Kjellsson, MC
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658280/ https://www.ncbi.nlm.nih.gov/pubmed/28575547 http://dx.doi.org/10.1002/psp4.12214

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