PharmML in Action: an Interoperable Language for Modeling and Simulation

PharmML1 is an XML‐based exchange format2, 3, 4 created with a focus on nonlinear mixed‐effect (NLME) models used in pharmacometrics,5, 6 but providing a very general framework that also allows describing mathematical and statistical models such as single‐subject or nonlinear and multivariate regres...

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Detalles Bibliográficos
Autores principales: Bizzotto, R, Comets, E, Smith, G, Yvon, F, Kristensen, NR, Swat, MJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Tutorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658288/
https://www.ncbi.nlm.nih.gov/pubmed/28575551
http://dx.doi.org/10.1002/psp4.12213
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author Bizzotto, R
Comets, E
Smith, G
Yvon, F
Kristensen, NR
Swat, MJ
author_facet Bizzotto, R
Comets, E
Smith, G
Yvon, F
Kristensen, NR
Swat, MJ
author_sort Bizzotto, R
collection PubMed
description PharmML1 is an XML‐based exchange format2, 3, 4 created with a focus on nonlinear mixed‐effect (NLME) models used in pharmacometrics,5, 6 but providing a very general framework that also allows describing mathematical and statistical models such as single‐subject or nonlinear and multivariate regression models. This tutorial provides an overview of the structure of this language, brief suggestions on how to work with it, and use cases demonstrating its power and flexibility.
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spelling pubmed-56582882017-10-27 PharmML in Action: an Interoperable Language for Modeling and Simulation Bizzotto, R Comets, E Smith, G Yvon, F Kristensen, NR Swat, MJ CPT Pharmacometrics Syst Pharmacol Tutorial PharmML1 is an XML‐based exchange format2, 3, 4 created with a focus on nonlinear mixed‐effect (NLME) models used in pharmacometrics,5, 6 but providing a very general framework that also allows describing mathematical and statistical models such as single‐subject or nonlinear and multivariate regression models. This tutorial provides an overview of the structure of this language, brief suggestions on how to work with it, and use cases demonstrating its power and flexibility. John Wiley and Sons Inc. 2017-09-15 2017-10 /pmc/articles/PMC5658288/ /pubmed/28575551 http://dx.doi.org/10.1002/psp4.12213 Text en © 2017 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Tutorial
Bizzotto, R
Comets, E
Smith, G
Yvon, F
Kristensen, NR
Swat, MJ
PharmML in Action: an Interoperable Language for Modeling and Simulation
title PharmML in Action: an Interoperable Language for Modeling and Simulation
title_full PharmML in Action: an Interoperable Language for Modeling and Simulation
title_fullStr PharmML in Action: an Interoperable Language for Modeling and Simulation
title_full_unstemmed PharmML in Action: an Interoperable Language for Modeling and Simulation
title_short PharmML in Action: an Interoperable Language for Modeling and Simulation
title_sort pharmml in action: an interoperable language for modeling and simulation
topic Tutorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658288/
https://www.ncbi.nlm.nih.gov/pubmed/28575551
http://dx.doi.org/10.1002/psp4.12213
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