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Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis
The Sox6 transcription factor is crucial for terminal maturation of definitive red blood cells. Sox6-null mouse fetuses present misshapen and nucleated erythrocytes, due to impaired actin assembly and cytoskeleton stability. These defects are accompanied with a reduced survival of Sox6(−/−) red bloo...
Autores principales: | Barbarani, Gloria, Ronchi, Antonella, Ruoppolo, Margherita, Santorelli, Lucia, Steinfelder, Robert, Elangovan, Sudharshan, Fugazza, Cristina, Caterino, Marianna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658338/ https://www.ncbi.nlm.nih.gov/pubmed/29074889 http://dx.doi.org/10.1038/s41598-017-14336-6 |
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