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The Role of Autophagy in Critical Illness-induced Liver Damage
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress, which activates the unfolded protein response (UPR), mediate critical illness-induced organ failure, often affecting the liver. Autophagy is known to alleviate both and suppressed or insufficiently activated autophagy in prolonged illn...
Autores principales: | Thiessen, Steven E., Derese, Inge, Derde, Sarah, Dufour, Thomas, Pauwels, Lies, Bekhuis, Youri, Pintelon, Isabel, Martinet, Wim, Van den Berghe, Greet, Vanhorebeek, Ilse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658339/ https://www.ncbi.nlm.nih.gov/pubmed/29074879 http://dx.doi.org/10.1038/s41598-017-14405-w |
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