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A method for the unbiased and efficient segmental labelling of RNA-binding proteins for structure and biophysics
Most eukaryotic RNA regulators recognise their RNA and protein partners by the combinatorial use of several RNA binding domains. Inter-domain dynamics and interactions play a key role in recognition and can be analysed by techniques such as NMR or FRET, provided that the information relative to the...
Autores principales: | Gallagher, Christopher, Burlina, Fabienne, Offer, John, Ramos, Andres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658380/ https://www.ncbi.nlm.nih.gov/pubmed/29074846 http://dx.doi.org/10.1038/s41598-017-13950-8 |
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