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Optimizing VAP scars after childhood cancer treatment: a pilot study

PURPOSE: Majority of pediatric cancer patients are treated with chemotherapy using Venous Access Ports (VAP). However, after surgical removal of the VAP prominent scars often remain and standard care is lacking. METHODS: Patients (N = 20) who were willing to participate were included prior to surgic...

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Autores principales: de Bruijn, C. M. A., Hoff, F. W., Bruggeman-Westermann, M. M., Terra, J. B., van Dijk, T. H., de Bont, E. S. J. M., Peek, A. M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658462/
https://www.ncbi.nlm.nih.gov/pubmed/28656469
http://dx.doi.org/10.1007/s00520-017-3787-4
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author de Bruijn, C. M. A.
Hoff, F. W.
Bruggeman-Westermann, M. M.
Terra, J. B.
van Dijk, T. H.
de Bont, E. S. J. M.
Peek, A. M. L.
author_facet de Bruijn, C. M. A.
Hoff, F. W.
Bruggeman-Westermann, M. M.
Terra, J. B.
van Dijk, T. H.
de Bont, E. S. J. M.
Peek, A. M. L.
author_sort de Bruijn, C. M. A.
collection PubMed
description PURPOSE: Majority of pediatric cancer patients are treated with chemotherapy using Venous Access Ports (VAP). However, after surgical removal of the VAP prominent scars often remain and standard care is lacking. METHODS: Patients (N = 20) who were willing to participate were included prior to surgical removal of their VAP. All patients were off therapy at time of VAP removal. Patients had the option to either choose from Dermatix®, meridian color therapy (MCT), or no additional treatment (NAT). Assessment of scars was done prior to and 3, 6, and 12 months after surgical VAP removal using Patient and Observer Scar Assessment Scales (POSAS) questionnaires. To identify whether Dermatix® or MCT is associated with better scar healing than without additional treatment, Mann-Whitney U tests were used. RESULTS: After 12 months of follow-up, both patients and dermatologists noted VAP scars had healed better after MCT compared to those without treatment (P = 0.010 for both POSAS patient and POSAS observer). No significant differences were observed between VAP scars after Dermatix® use and those with no treatment. CONCLUSIONS: Scar healing after MCT significantly improved, whereas Dermatix® treatment showed no significant differences compared to NAT. To translate this to daily care, a larger prospective study is needed to validate these findings.
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spelling pubmed-56584622017-11-03 Optimizing VAP scars after childhood cancer treatment: a pilot study de Bruijn, C. M. A. Hoff, F. W. Bruggeman-Westermann, M. M. Terra, J. B. van Dijk, T. H. de Bont, E. S. J. M. Peek, A. M. L. Support Care Cancer Original Article PURPOSE: Majority of pediatric cancer patients are treated with chemotherapy using Venous Access Ports (VAP). However, after surgical removal of the VAP prominent scars often remain and standard care is lacking. METHODS: Patients (N = 20) who were willing to participate were included prior to surgical removal of their VAP. All patients were off therapy at time of VAP removal. Patients had the option to either choose from Dermatix®, meridian color therapy (MCT), or no additional treatment (NAT). Assessment of scars was done prior to and 3, 6, and 12 months after surgical VAP removal using Patient and Observer Scar Assessment Scales (POSAS) questionnaires. To identify whether Dermatix® or MCT is associated with better scar healing than without additional treatment, Mann-Whitney U tests were used. RESULTS: After 12 months of follow-up, both patients and dermatologists noted VAP scars had healed better after MCT compared to those without treatment (P = 0.010 for both POSAS patient and POSAS observer). No significant differences were observed between VAP scars after Dermatix® use and those with no treatment. CONCLUSIONS: Scar healing after MCT significantly improved, whereas Dermatix® treatment showed no significant differences compared to NAT. To translate this to daily care, a larger prospective study is needed to validate these findings. Springer Berlin Heidelberg 2017-06-28 2017 /pmc/articles/PMC5658462/ /pubmed/28656469 http://dx.doi.org/10.1007/s00520-017-3787-4 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
de Bruijn, C. M. A.
Hoff, F. W.
Bruggeman-Westermann, M. M.
Terra, J. B.
van Dijk, T. H.
de Bont, E. S. J. M.
Peek, A. M. L.
Optimizing VAP scars after childhood cancer treatment: a pilot study
title Optimizing VAP scars after childhood cancer treatment: a pilot study
title_full Optimizing VAP scars after childhood cancer treatment: a pilot study
title_fullStr Optimizing VAP scars after childhood cancer treatment: a pilot study
title_full_unstemmed Optimizing VAP scars after childhood cancer treatment: a pilot study
title_short Optimizing VAP scars after childhood cancer treatment: a pilot study
title_sort optimizing vap scars after childhood cancer treatment: a pilot study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658462/
https://www.ncbi.nlm.nih.gov/pubmed/28656469
http://dx.doi.org/10.1007/s00520-017-3787-4
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