Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices

A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lun...

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Autores principales: Saito, Hiroaki, Ohmori, Masayasu, Iwamuro, Masaya, Tanaka, Takehiro, Wada, Nozomu, Yasunaka, Tetsuya, Takaki, Akinobu, Okada, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658523/
https://www.ncbi.nlm.nih.gov/pubmed/28883247
http://dx.doi.org/10.2169/internalmedicine.8768-16
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author Saito, Hiroaki
Ohmori, Masayasu
Iwamuro, Masaya
Tanaka, Takehiro
Wada, Nozomu
Yasunaka, Tetsuya
Takaki, Akinobu
Okada, Hiroyuki
author_facet Saito, Hiroaki
Ohmori, Masayasu
Iwamuro, Masaya
Tanaka, Takehiro
Wada, Nozomu
Yasunaka, Tetsuya
Takaki, Akinobu
Okada, Hiroyuki
author_sort Saito, Hiroaki
collection PubMed
description A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lungs, heart, and skin. Although fat deposition was predominant, non-caseating granuloma and cirrhotic changes were found in the liver. Non-caseating granuloma was also identified in a biopsy specimen from minute depressions of the gastric folds. This case illustrates the rare involvement of the digestive system in a case of systemic sarcoidosis.
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spelling pubmed-56585232017-10-27 Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices Saito, Hiroaki Ohmori, Masayasu Iwamuro, Masaya Tanaka, Takehiro Wada, Nozomu Yasunaka, Tetsuya Takaki, Akinobu Okada, Hiroyuki Intern Med Case Report A 46-year-old woman presented with massive hematemesis, caused by the rupture of esophageal varices. The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites. A diagnosis of systemic sarcoidosis was made based on biopsies of the liver, stomach, lungs, heart, and skin. Although fat deposition was predominant, non-caseating granuloma and cirrhotic changes were found in the liver. Non-caseating granuloma was also identified in a biopsy specimen from minute depressions of the gastric folds. This case illustrates the rare involvement of the digestive system in a case of systemic sarcoidosis. The Japanese Society of Internal Medicine 2017-09-06 2017-10-01 /pmc/articles/PMC5658523/ /pubmed/28883247 http://dx.doi.org/10.2169/internalmedicine.8768-16 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Saito, Hiroaki
Ohmori, Masayasu
Iwamuro, Masaya
Tanaka, Takehiro
Wada, Nozomu
Yasunaka, Tetsuya
Takaki, Akinobu
Okada, Hiroyuki
Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices
title Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices
title_full Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices
title_fullStr Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices
title_full_unstemmed Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices
title_short Hepatic and Gastric Involvement in a Case of Systemic Sarcoidosis Presenting with Rupture of Esophageal Varices
title_sort hepatic and gastric involvement in a case of systemic sarcoidosis presenting with rupture of esophageal varices
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658523/
https://www.ncbi.nlm.nih.gov/pubmed/28883247
http://dx.doi.org/10.2169/internalmedicine.8768-16
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