Genetic variants and phylogenetic analysis of Haemophilus parasuis (HPS) OMPP2 detected in Sichuan, China from 2013 to 2015

To investigate the genetic variation in Haemophilus parasuis (HPS) in Sichuan, China, 11 isolates were analyzed based on the outer membrane protein P2 (OMPP2) sequence. Sequence analysis showed that the 11 isolates shared 93.0 to 100% nucleotide homology with 15 reference strains, and the consistenc...

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Detalles Bibliográficos
Autores principales: WU, Xulong, XIAO, Lu, WANG, Yin, YAO, Xueping, YANG, Zexiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Bacteriology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658552/
https://www.ncbi.nlm.nih.gov/pubmed/28824043
http://dx.doi.org/10.1292/jvms.16-0519
Descripción
Sumario:To investigate the genetic variation in Haemophilus parasuis (HPS) in Sichuan, China, 11 isolates were analyzed based on the outer membrane protein P2 (OMPP2) sequence. Sequence analysis showed that the 11 isolates shared 93.0 to 100% nucleotide homology with 15 reference strains, and the consistency between the 26 strains was 89.0%. The isolates of HPS-1, 2, 4, 5, 6, 7, 8, 10 and 11 had a 69-base deletion from 770 base pairs (bp) to 850 bp, which was infrequent in China. The phylogenetic tree showed that HPS-3 and HPS-8 had closer relationships with European and Japanese strains, but shared 98.7% nucleotide homology with the SW114 Japanese strain.

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