Repeated phlebotomies decrease body iron storage in adult dogs

The aim of the present study was to determine changes in body iron storage in adult dogs following phlebotomy. We performed repeated phlebotomies by removing 1% body weight (approximately 10% of the total blood volume) weekly for a total of 12 times using adult beagle dogs without an iron-restricted...

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Detalles Bibliográficos
Autores principales: CHIKAZAWA, Seishiro, HOSHI, Fumio, KANAI, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658553/
https://www.ncbi.nlm.nih.gov/pubmed/28804090
http://dx.doi.org/10.1292/jvms.17-0118
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author CHIKAZAWA, Seishiro
HOSHI, Fumio
KANAI, Kazutaka
author_facet CHIKAZAWA, Seishiro
HOSHI, Fumio
KANAI, Kazutaka
author_sort CHIKAZAWA, Seishiro
collection PubMed
description The aim of the present study was to determine changes in body iron storage in adult dogs following phlebotomy. We performed repeated phlebotomies by removing 1% body weight (approximately 10% of the total blood volume) weekly for a total of 12 times using adult beagle dogs without an iron-restricted diet. After treatment, stored iron was decreased, as demonstrated by gradual reductions in serum ferritin levels and hepatic iron contents. Anemia and abnormalities in blood chemistry analysis were not observed; therefore, this method was considered safe and useful for control of stored iron levels in adult dogs.
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spelling pubmed-56585532017-11-01 Repeated phlebotomies decrease body iron storage in adult dogs CHIKAZAWA, Seishiro HOSHI, Fumio KANAI, Kazutaka J Vet Med Sci Internal Medicine The aim of the present study was to determine changes in body iron storage in adult dogs following phlebotomy. We performed repeated phlebotomies by removing 1% body weight (approximately 10% of the total blood volume) weekly for a total of 12 times using adult beagle dogs without an iron-restricted diet. After treatment, stored iron was decreased, as demonstrated by gradual reductions in serum ferritin levels and hepatic iron contents. Anemia and abnormalities in blood chemistry analysis were not observed; therefore, this method was considered safe and useful for control of stored iron levels in adult dogs. The Japanese Society of Veterinary Science 2017-08-11 2017-10 /pmc/articles/PMC5658553/ /pubmed/28804090 http://dx.doi.org/10.1292/jvms.17-0118 Text en ©2017 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Internal Medicine
CHIKAZAWA, Seishiro
HOSHI, Fumio
KANAI, Kazutaka
Repeated phlebotomies decrease body iron storage in adult dogs
title Repeated phlebotomies decrease body iron storage in adult dogs
title_full Repeated phlebotomies decrease body iron storage in adult dogs
title_fullStr Repeated phlebotomies decrease body iron storage in adult dogs
title_full_unstemmed Repeated phlebotomies decrease body iron storage in adult dogs
title_short Repeated phlebotomies decrease body iron storage in adult dogs
title_sort repeated phlebotomies decrease body iron storage in adult dogs
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658553/
https://www.ncbi.nlm.nih.gov/pubmed/28804090
http://dx.doi.org/10.1292/jvms.17-0118
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