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A 2-base insertion in exon 5 is a common mutation of the TP53 gene in dogs with histiocytic sarcoma

Canine histiocytic sarcoma (HS) is a malignancy originating from the histiocytic cell lineage and characterized by poor response to chemotherapy and short survival time. Mutation of the TP53 gene and its association with poor prognosis has been reported in several canine tumors. However, the mutatio...

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Detalles Bibliográficos
Autores principales: ASADA, Hajime, TSUBOI, Masaya, CHAMBERS, James K., UCHIDA, Kazuyuki, TOMIYASU, Hirotaka, GOTO-KOSHINO, Yuko, OHNO, Koichi, TSUJIMOTO, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658567/
https://www.ncbi.nlm.nih.gov/pubmed/28867679
http://dx.doi.org/10.1292/jvms.17-0197