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A 2-base insertion in exon 5 is a common mutation of the TP53 gene in dogs with histiocytic sarcoma
Canine histiocytic sarcoma (HS) is a malignancy originating from the histiocytic cell lineage and characterized by poor response to chemotherapy and short survival time. Mutation of the TP53 gene and its association with poor prognosis has been reported in several canine tumors. However, the mutatio...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Japanese Society of Veterinary Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658567/ https://www.ncbi.nlm.nih.gov/pubmed/28867679 http://dx.doi.org/10.1292/jvms.17-0197 |