MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability

Gene expression analysis of The Cancer Genome Atlas (TCGA) breast cancer data set show that miR-20a is upregulated in human breast cancer, especially in triple-negative subtype. Gene Set Enrichment Analysis suggests that miR-20a expression negatively correlates with the autophagy/lysosome pathway. W...

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Detalles Bibliográficos
Autores principales: Liu, L, He, J, Wei, X, Wan, G, Lao, Y, Xu, W, Li, Z, Hu, H, Hu, Z, Luo, X, Wu, J, Xie, W, Zhang, Y, Xu, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658668/
https://www.ncbi.nlm.nih.gov/pubmed/28628113
http://dx.doi.org/10.1038/onc.2017.193

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