The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model

Neuronal network dysfunction and cognitive decline constitute the most prominent features of Alzheimer’s disease (AD), although mechanisms causing such impairments are yet to be determined. Here we report that virus-mediated delivery of the active spliced transcription factor X-Box binding protein 1...

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Detalles Bibliográficos
Autores principales: Cissé, M, Duplan, E, Lorivel, T, Dunys, J, Bauer, C, Meckler, X, Gerakis, Y, Lauritzen, I, Checler, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658671/
https://www.ncbi.nlm.nih.gov/pubmed/27646263
http://dx.doi.org/10.1038/mp.2016.152

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