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Ready, Set…Poised!: Polycomb target genes are bound by poised RNA polymerase II throughout differentiation
In embryonic stem cells (ESCs), silent genes with major developmental functions display a unique epigenetic state in which strong and broad binding by Polycomb repressive complexes (PRCs) is accompanied by the presence of poised RNA polymerase II (RNAPII) and activating histone marks (e.g. H3K4me3)...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658701/ https://www.ncbi.nlm.nih.gov/pubmed/29061670 http://dx.doi.org/10.15252/msb.20177968 |