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Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis
The identification of the TAR DNA-binding protein 43 (TDP-43) as the ubiquitinated cytoplasmic inclusions in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) confirmed that these two diseases share similar mechanisms, likely to be linked to the abnormal hyperphosphory...
Autores principales: | Tan, Rachel H., Yang, Yue, Kim, Woojin S., Dobson-Stone, Carol, Kwok, John B., Kiernan, Matthew C., Halliday, Glenda M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658959/ https://www.ncbi.nlm.nih.gov/pubmed/29078806 http://dx.doi.org/10.1186/s40478-017-0480-2 |
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