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Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain

BACKGROUND: Regulators of G-protein signaling (RGS) are major physiological modulators of G-protein-coupled receptors (GPCR) signaling. Several GPCRs expressed in both neurons and astrocytes participate in the central control of pain processing, and the reduced efficacy of analgesics in neuropathic...

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Detalles Bibliográficos
Autores principales: Doyen, Pierre J., Vergouts, Maxime, Pochet, Amandine, Desmet, Nathalie, van Neerven, Sabien, Brook, Gary, Hermans, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658970/
https://www.ncbi.nlm.nih.gov/pubmed/29078779
http://dx.doi.org/10.1186/s12974-017-0971-x