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Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10

BACKGROUND: Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used Gene Set Enrichment Analysis (GSEA) and Ingenuity Pathway Analysis (IPA) to analyze previously generated DNA microarray data from hu...

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Detalles Bibliográficos
Autores principales:	Gopinathan, Unni, Øvstebø, Reidun, Brusletto, Berit Sletbakk, Olstad, Ole Kristoffer, Kierulf, Peter, Brandtzaeg, Petter, Berg, Jens Petter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659018/ https://www.ncbi.nlm.nih.gov/pubmed/29078758 http://dx.doi.org/10.1186/s12865-017-0229-5

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