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Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis

The molecular mechanisms underlying dysregulated wild type (wt) p53 in multiple myeloma (MM) have been subjects of intense investigation for years. Indeed, correlation of rarely occurring TP53 gene mutations or deletions with adverse clinical outcomes in MM patients is strongly established, while in...

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Detalles Bibliográficos
Autores principales: Abdi, Jahangir, Rastgoo, Nasrin, Li, Lihong, Chen, Wenming, Chang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659022/
https://www.ncbi.nlm.nih.gov/pubmed/29073933
http://dx.doi.org/10.1186/s13045-017-0538-4