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Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis
The molecular mechanisms underlying dysregulated wild type (wt) p53 in multiple myeloma (MM) have been subjects of intense investigation for years. Indeed, correlation of rarely occurring TP53 gene mutations or deletions with adverse clinical outcomes in MM patients is strongly established, while in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659022/ https://www.ncbi.nlm.nih.gov/pubmed/29073933 http://dx.doi.org/10.1186/s13045-017-0538-4 |