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Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru

BACKGROUND: Previous studies have shown that hypertension is a risk factor for cognitive impairment, but whether this association is also present in extremely poor populations in Low Middle Income Countries settings remains to be studied. Understanding other drivers of cognitive impairment in this u...

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Autores principales: Lazo-Porras, Maria, Ortiz-Soriano, Victor, Moscoso-Porras, Miguel, Runzer-Colmenares, Fernando M., Málaga, German, Jaime Miranda, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659043/
https://www.ncbi.nlm.nih.gov/pubmed/29073885
http://dx.doi.org/10.1186/s12877-017-0628-8
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author Lazo-Porras, Maria
Ortiz-Soriano, Victor
Moscoso-Porras, Miguel
Runzer-Colmenares, Fernando M.
Málaga, German
Jaime Miranda, J.
author_facet Lazo-Porras, Maria
Ortiz-Soriano, Victor
Moscoso-Porras, Miguel
Runzer-Colmenares, Fernando M.
Málaga, German
Jaime Miranda, J.
author_sort Lazo-Porras, Maria
collection PubMed
description BACKGROUND: Previous studies have shown that hypertension is a risk factor for cognitive impairment, but whether this association is also present in extremely poor populations in Low Middle Income Countries settings remains to be studied. Understanding other drivers of cognitive impairment in this unique population also merits attention. METHODS: We performed a secondary analysis using data from the “Encuesta de Salud y Bienestar del Adulto Mayor”, a regional survey conducted in an extremely poor population of people older than 65 years old from 12 Peruvian cities in 2012. The outcome variable was cognitive impairment, determined by a score of ≤7 in the modified Mini-Mental State Examination. The exposure was self-reported hypertension status. Variables such as age, gender, controlled hypertension, education level, occupation, depression and area of living (rural/urban) were included in the adjusted analysis. We used Poisson regression with robust variance to calculate prevalence ratios (PR) and 95% confidence interval (95% CI) adjusting for confounders. RESULTS: Data from 3842 participants was analyzed, 51.8% were older than 70 years, and 45.6% were females. The prevalence of cognitive impairment was 1.7% (95% CI 1.3%–2.1%). There was no significant difference on the prevalence of cognitive impairment between the group of individuals with hypertension in comparison with those without hypertension (PR = 0.64, 95% CI 0.33–1.23). CONCLUSIONS: The association described between hypertension and cognitive impairment was not found in a sample of extremely poor Peruvian older adults. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12877-017-0628-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-56590432017-11-01 Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru Lazo-Porras, Maria Ortiz-Soriano, Victor Moscoso-Porras, Miguel Runzer-Colmenares, Fernando M. Málaga, German Jaime Miranda, J. BMC Geriatr Research Article BACKGROUND: Previous studies have shown that hypertension is a risk factor for cognitive impairment, but whether this association is also present in extremely poor populations in Low Middle Income Countries settings remains to be studied. Understanding other drivers of cognitive impairment in this unique population also merits attention. METHODS: We performed a secondary analysis using data from the “Encuesta de Salud y Bienestar del Adulto Mayor”, a regional survey conducted in an extremely poor population of people older than 65 years old from 12 Peruvian cities in 2012. The outcome variable was cognitive impairment, determined by a score of ≤7 in the modified Mini-Mental State Examination. The exposure was self-reported hypertension status. Variables such as age, gender, controlled hypertension, education level, occupation, depression and area of living (rural/urban) were included in the adjusted analysis. We used Poisson regression with robust variance to calculate prevalence ratios (PR) and 95% confidence interval (95% CI) adjusting for confounders. RESULTS: Data from 3842 participants was analyzed, 51.8% were older than 70 years, and 45.6% were females. The prevalence of cognitive impairment was 1.7% (95% CI 1.3%–2.1%). There was no significant difference on the prevalence of cognitive impairment between the group of individuals with hypertension in comparison with those without hypertension (PR = 0.64, 95% CI 0.33–1.23). CONCLUSIONS: The association described between hypertension and cognitive impairment was not found in a sample of extremely poor Peruvian older adults. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12877-017-0628-8) contains supplementary material, which is available to authorized users. BioMed Central 2017-10-26 /pmc/articles/PMC5659043/ /pubmed/29073885 http://dx.doi.org/10.1186/s12877-017-0628-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Lazo-Porras, Maria
Ortiz-Soriano, Victor
Moscoso-Porras, Miguel
Runzer-Colmenares, Fernando M.
Málaga, German
Jaime Miranda, J.
Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru
title Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru
title_full Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru
title_fullStr Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru
title_full_unstemmed Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru
title_short Cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in Peru
title_sort cognitive impairment and hypertension in older adults living in extreme poverty: a cross-sectional study in peru
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659043/
https://www.ncbi.nlm.nih.gov/pubmed/29073885
http://dx.doi.org/10.1186/s12877-017-0628-8
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