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Brain Injury-Induced Synaptic Reorganization in Hilar Inhibitory Neurons Is Differentially Suppressed by Rapamycin

Following traumatic brain injury (TBI), treatment with rapamycin suppresses mammalian (mechanistic) target of rapamycin (mTOR) activity and specific components of hippocampal synaptic reorganization associated with altered cortical excitability and seizure susceptibility. Reemergence of seizures aft...

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Detalles Bibliográficos
Autores principales: Butler, Corwin R., Boychuk, Jeffery A., Smith, Bret N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659239/
https://www.ncbi.nlm.nih.gov/pubmed/29085896
http://dx.doi.org/10.1523/ENEURO.0134-17.2017