A practical approach to pancreatic cancer immunotherapy using resected tumor lysate vaccines processed to express α-gal epitopes

OBJECTIVES: Single-agent immunotherapy is ineffective against poorly immunogenic cancers, including pancreatic ductal adenocarcinoma (PDAC). The aims of this study were to demonstrate the feasibility of production of novel autologous tumor lysate vaccines from resected PDAC tumors, and verify vaccin...

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Detalles Bibliográficos
Autores principales: Furukawa, Kenta, Tanemura, Masahiro, Miyoshi, Eiji, Eguchi, Hidetoshi, Nagano, Hiroaki, Matsunami, Katsuyoshi, Nagaoka, Satoshi, Yamada, Daisaku, Asaoka, Tadafumi, Noda, Takehiro, Wada, Hiroshi, Kawamoto, Koichi, Goto, Kunihito, Taniyama, Kiyomi, Mori, Masaki, Doki, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659602/
https://www.ncbi.nlm.nih.gov/pubmed/29077749
http://dx.doi.org/10.1371/journal.pone.0184901

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