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A novel controller based on state-transition models for closed-loop vagus nerve stimulation: Application to heart rate regulation

Vagus nerve stimulation (VNS) is an established adjunctive therapy for pharmacologically refractory epilepsy and depression and is currently in active clinical research for other applications. In current clinical studies, VNS is delivered in an open-loop approach, where VNS parameters are defined du...

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Detalles Bibliográficos
Autores principales: Romero-Ugalde, Hector M., Le Rolle, Virginie, Bonnet, Jean-Luc, Henry, Christine, Bel, Alain, Mabo, Philippe, Carrault, Guy, Hernández, Alfredo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659642/
https://www.ncbi.nlm.nih.gov/pubmed/29077707
http://dx.doi.org/10.1371/journal.pone.0186068