TSH/IGF-1 Receptor Cross-Talk Rapidly Activates Extracellular Signal-Regulated Kinases in Multiple Cell Types

We previously showed that thyrotropin (TSH)/insulinlike growth factor (IGF)-1 receptor cross-talk appears to be involved in Graves’ orbitopathy (GO) pathogenesis and upregulation of thyroid-specific genes in human thyrocytes. In orbital fibroblasts from GO patients, coadministration of TSH and IGF-1...

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Detalles Bibliográficos
Autores principales: Krieger, Christine C., Perry, Joseph D., Morgan, Sarah J., Kahaly, George J., Gershengorn, Marvin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659693/
https://www.ncbi.nlm.nih.gov/pubmed/28938449
http://dx.doi.org/10.1210/en.2017-00528

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