GATOR1 regulates nitrogenic cataplerotic reactions of the mitochondrial TCA cycle

The GATOR1/SEACIT complex consisting of Iml1-Npr2-Npr3 inhibits Target of Rapamycin Complex 1 (TORC1) in response to amino acid insufficiency. In glucose medium, Saccharomyces cerevisiae mutants lacking the function of this complex grow poorly in the absence of amino acid supplementation, despite ha...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Sutter, Benjamin M., Shi, Lei, Tu, Benjamin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659745/
https://www.ncbi.nlm.nih.gov/pubmed/28920930
http://dx.doi.org/10.1038/nchembio.2478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659745/
https://www.ncbi.nlm.nih.gov/pubmed/28920930
http://dx.doi.org/10.1038/nchembio.2478

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