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Bioluminescence imaging of G protein-coupled receptor activation in living mice
G protein-coupled receptors (GPCRs), a superfamily of cell-surface receptors involved in virtually all physiological processes, are the major target class for approved drugs. Imaging GPCR activation in real time in living animals would provide a powerful way to study their role in biology and diseas...
Autores principales: | Kono, Mari, Conlon, Elizabeth G., Lux, Samantha Y., Yanagida, Keisuke, Hla, Timothy, Proia, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660082/ https://www.ncbi.nlm.nih.gov/pubmed/29079828 http://dx.doi.org/10.1038/s41467-017-01340-7 |
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