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Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs

Hyperoxia-induced acute lung injury (HALI) is a key contributor to the pathogenesis of bronchopulmonary dysplasia (BPD) in neonates, for which no specific preventive or therapeutic agent is available. Here we show that lung micro-RNA (miR)-34a levels are significantly increased in lungs of neonatal...

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Detalles Bibliográficos
Autores principales: Syed, Mansoor, Das, Pragnya, Pawar, Aishwarya, Aghai, Zubair H., Kaskinen, Anu, Zhuang, Zhen W., Ambalavanan, Namasivayam, Pryhuber, Gloria, Andersson, Sture, Bhandari, Vineet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660088/
https://www.ncbi.nlm.nih.gov/pubmed/29079808
http://dx.doi.org/10.1038/s41467-017-01349-y

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