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A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1

BACKGROUND: Anti-angiogenic therapies, targeting VEGF, are a promising treatment for hepatocellular carcinoma (HCC). To enhance this potential therapy, identification of novel targets in this pathway is of major interest. Nitric oxide (NO) plays a crucial role in VEGF-dependent angiogenesis. NO prod...

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Detalles Bibliográficos
Autores principales: Buijs, Nikki, Oosterink, J. Efraim, Jessup, Morgan, Schierbeek, Henk, Stolz, Donna B., Houdijk, Alexander P., Geller, David A., van Leeuwen, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660142/
https://www.ncbi.nlm.nih.gov/pubmed/28741166
http://dx.doi.org/10.1007/s10456-017-9567-4