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Optimization of large animal MI models; a systematic analysis of control groups from preclinical studies
Large animal models are essential for the development of novel therapeutics for myocardial infarction. To optimize translation, we need to assess the effect of experimental design on disease outcome and model experimental design to resemble the clinical course of MI. The aim of this study is therefo...
Autores principales: | Zwetsloot, P. P., Kouwenberg, L. H. J. A., Sena, E. S., Eding, J. E., den Ruijter, H. M., Sluijter, J. P. G., Pasterkamp, G., Doevendans, P. A., Hoefer, I. E., Chamuleau, S. A. J., van Hout, G. P. J., Jansen of Lorkeers, S. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660150/ https://www.ncbi.nlm.nih.gov/pubmed/29079786 http://dx.doi.org/10.1038/s41598-017-14294-z |
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