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Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors
Harnessing immune system to treat cancer requires simultaneous generation of tumor-specific CTLs and curtailment of tumor immunosuppressive environment. Here, we developed an immunotherapeutic regimen capable of eliminating large established mouse tumors using HMGN1, a DC-activating TLR4 agonist cap...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660153/ https://www.ncbi.nlm.nih.gov/pubmed/29079801 http://dx.doi.org/10.1038/s41598-017-14655-8 |