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Pharmacological preconditioning with gemfibrozil preserves cardiac function after heart transplantation

While heart transplantation (HTX) is the definitive therapy of heart failure, donor shortage is emerging. Pharmacological activation of soluble guanylate cyclase (sGC) and increased cGMP-signalling have been reported to have cardioprotective properties. Gemfibrozil has recently been shown to exert s...

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Detalles Bibliográficos
Autores principales: Benke, Kálmán, Mátyás, Csaba, Sayour, Alex Ali, Oláh, Attila, Németh, Balázs Tamás, Ruppert, Mihály, Szabó, Gábor, Kökény, Gábor, Horváth, Eszter Mária, Hartyánszky, István, Szabolcs, Zoltán, Merkely, Béla, Radovits, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660179/
https://www.ncbi.nlm.nih.gov/pubmed/29079777
http://dx.doi.org/10.1038/s41598-017-14587-3

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